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MYD88 bindet nach Aktivierung an die Toll-like Rezeptoren und bildet dort ein Gerüst für die Bindung von IRAK - Kinasen. Es entsteht ein filamentöser Komplex aus .
Radiation therapy induces immunogenic cell death in cancer cells, whereby released endogenous adjuvants are sensed by immune cells to direct adaptive immune .Get better batch-to-batch reproducibility with a recombinant antibody. Anti-MyD88 antibody [EPR21824] (ab219413) Research with confidence – consistent and reproducible results .
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MyD88 and MAL are Toll-like receptor (TLR) adaptors that signal to induce pro-inflammatory cytokine production. We previously observed that the TIR domain of MAL (MALTIR) forms filaments in vitro .
Die MYD88-L265P-Mutation ist eine Mutation, die bei bestimmten Lymphomen auftritt. Es handelt sich um eine Punktmutation im Gen des Adapterproteins MYD88, die dazu führt, dass an Position 265 Leucin gegen Prolin ausgetauscht wird.
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